• Thumbnail for JAG1
    Jagged1 (JAG1) is one of five cell surface proteins (ligands) that interact with four receptors in the mammalian Notch signaling pathway. The Notch signaling...
    22 KB (2,693 words) - 23:18, 13 April 2024
  • Thumbnail for Alagille syndrome
    in either JAG1 (Jagged1) or NOTCH2 (Notch homolog 2). In the majority of people with ALGS, the gene mutation occurs in the JAG1 gene. The JAG1 mutation...
    20 KB (2,099 words) - 06:25, 7 July 2024
  • Thumbnail for Ovarian cancer
    with CSF-1 50% FOXL2 point mutation (402 C to G) adult granulosa cell ~100% JAG1 amplification 2% JAG2 amplification 3% KRAS amplification mucinous and low-grade...
    196 KB (20,972 words) - 19:41, 10 July 2024
  • Thumbnail for Tetralogy of Fallot
    include: JAG1 codes for ligands within the Notch family of proteins and is highly expressed in the developing heart. Mutations of the JAG1 gene can lead...
    78 KB (8,320 words) - 15:59, 15 January 2024
  • recessive Adrenoleukodystrophy ABCD1 (X) recessive 1:17,000 Alagille syndrome JAG1, NOTCH2 dominant 1:30,000-50,000 ADULT syndrome TP63 dominant Aicardi–Goutières...
    42 KB (969 words) - 16:02, 3 April 2024
  • Thumbnail for Aidonia
    clash for classmates and friends, writing his own lyrics and formed the JAG1 (Jah A Guide)(JOP) crew with friends. After being expelled, he relocated...
    5 KB (529 words) - 20:16, 19 June 2024
  • Thumbnail for Sertoli cell
    immune cells) B7/H1 – decreasing proliferation of effector T-cells Jagged1 (JAG1) – induction of Foxp3 transcription factor expression in naive T lymphocytes...
    26 KB (3,062 words) - 14:58, 7 April 2024
  • CD339 JAG1 (Jagged 1). One of five cell surface proteins (ligands) that interact with 4 receptors in the mammalian Notch signaling pathway. The JAG1 gene...
    96 KB (467 words) - 06:58, 14 October 2022
  • Thumbnail for Syndromes affecting the heart
    genetic (Autosomal dominant inheritance: loss of function mutations in either JAG1 or NOTCH2) Congenital heart problems e.g. pulmonary artery stenosis (common)...
    6 KB (113 words) - 09:28, 23 January 2021
  • Thumbnail for K. Christopher Garcia
    Delta-like 4 (DLL4) and Jagged1 (Jag1) as a means of stabilizing the complexes for co-crystallization. Notch1-DLL4 and Notch1-Jag1 structures were determined...
    23 KB (2,278 words) - 18:08, 8 May 2024