Tolcapone, sold under the brand name Tasmar, is a medication used to treat Parkinson's disease (PD). It is a selective, potent and reversible nitrocatechol-type...

Marketed Entacapone (Comtan, Comtess, Stalevo) Opicapone (Ongentys) Tolcapone (Tasmar) Not marketed Nebicapone (BIA 3-202) Neluxicapone Nitecapone (OR-462)...

and tolcapone. The drug shows peripheral selectivity and does not significantly act in the brain. In contrast to the centrally penetrant tolcapone, nebicapone...

and tolcapone ... have been demonstrated to reduce the dose of L-DOPA required and also cause improvement in clinical symptoms, although tolcapone emerged...

opicapone, and tolcapone, which are used in the treatment of Parkinson's disease. Entacapone and opicapone are peripherally selective, but tolcapone significantly...

tolcapone "orphan drug status" in studies aiming at the treatment of transthyretin familial amyloidosis (ATTR). However, as of 2015[update] tolcapone...

structurally related to other catechol COMT inhibitors like entacapone, tolcapone, and nebicapone. COMT inhibitors are used in conjunction with levodopa...

selective monoamine oxidase B (MAO-B) inhibitor; but see more below), tolcapone (a centrally-acting catechol-O-methyltransferase (COMT) inhibitor), and...

of the sympathetic nervous system.[citation needed] Some drugs, like tolcapone (a central COMT-inhibitor), raise the levels of all the catecholamines...

Tiagabine Tianeptine Tiapride Thioproperazine Thioridazine Thiothixene Tolcapone Topiramate Tranylcypromine Trazodone Triclofos Trifluoperazine Trifluperidol...