Muromonab-CD3 (brand name Orthoclone OKT3, marketed by Janssen-Cilag) is an immunosuppressant medication given to reduce acute rejection in people with...
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antibodies reducing the effectiveness of muromonab-CD3. Muromonab-CD3 can cause excessive immunosuppression. Although CD3 antibodies act more specifically than...
29 KB (3,378 words) - 13:22, 5 September 2024
anti-CD3 monoclonal antibody is one that binds to CD3 on the surface of T cells. They are immunosuppresive drugs. The first to be approved was muromonab-CD3...
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Medicine Nobel Prize for their discovery together with Niels Kaj Jerne. Muromonab-CD3 was the first monoclonal antibody to be approved for clinical use in...
38 KB (3,088 words) - 05:02, 8 August 2024
activate the immune system through receptors on white blood cells. Muromonab-CD3, an anti-CD3 monoclonal antibody intended to suppress the immune system to...
24 KB (2,551 words) - 01:16, 25 June 2024
Retrieved 3 January 2023. Wilde, Michelle I.; Goa, Karen L. (1 May 1996). "Muromonab CD3". Drugs. 51 (5): 865–894. doi:10.2165/00003495-199651050-00010. ISSN 1179-1950...
136 KB (4,020 words) - 07:14, 15 August 2024
lymphoproliferative disorder. Such antibodies include ATG, ALG and OKT3 (muromonab-CD3).[citation needed] Polyclonal PTLD may form tumor masses and present...
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won the Nobel Prize for Medicine in 1984 for their work. Soon after, muromonab-CD3 became the first fully licensed monoclonal antibody in 1986 for its...
28 KB (3,327 words) - 19:25, 25 July 2024
IL-23 Lebrikizumab Ustekinumab IL-17A Secukinumab Cellular target CD3 Muromonab-CD3 Otelixizumab Teplizumab Visilizumab CD4 Clenoliximab Keliximab Zanolimumab...
7 KB (299 words) - 13:45, 27 April 2024
1 syndrome – multiple myeloma – multiple sclerosis – multiplicity – muromonab-CD3 monoclonal antibody – musculoskeletal – mycophenolate mofetil – mycosis...
69 KB (5,119 words) - 11:20, 3 June 2024