French
Deutsch(Myelin basic protein)-arginine N-methyltransferase
| [myelin basic protein]-arginine N-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.126 | ||||||||
| CAS no. | 9055-07-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a [myelin basic protein]-arginine N-methyltransferase (EC 2.1.1.126) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + [myelin basic protein]-arginine S-adenosyl-L-homocysteine + [myelin basic protein]-Nomega-methyl-arginine
Thus, the two substrates of this enzyme are S-adenosyl methionine and myelin basic protein-arginine, whereas its two products are S-adenosylhomocysteine and myelin basic protein-Nomega-methyl-arginine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:[myelin-basic-protein]-arginine Nomega-methyltransferase. Other names in common use include myelin basic protein methylase I, protein methylase I, S-adenosyl-L-methionine:[myelin-basic-protein]-arginine, and omega-N-methyltransferase.
References
[edit]- Ghosh SK, Paik WK, Kim S (1988). "Purification and molecular identification of two protein methylases I from calf brain. Myelin basic protein- and histone-specific enzyme". J. Biol. Chem. 263 (35): 19024–33. PMID 2461933.
