Coibamide A
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Names | |
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IUPAC name [(2S)-1-[[(2S)-1-[[(2S)-1-[[(3S,6S,9S,12S,15S,18S,21S,22R)-15-[(2S)-butan-2-yl]-18-(methoxymethyl)-6-[(4-methoxyphenyl)methyl]-3,4,10,12,16,19,22-heptamethyl-9-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]-methylamino]-4-methyl-1-oxopentan-2-yl]-methylamino]-3-methoxy-1-oxopropan-2-yl]-methylamino]-3-methyl-1-oxobutan-2-yl] (2S)-2-(dimethylamino)-3-methylbutanoate | |
Identifiers | |
3D model (JSmol) | |
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PubChem CID | |
CompTox Dashboard (EPA) | |
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Properties | |
C65H110N10O16 | |
Molar mass | 1287.649 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Coibamide A is an antiproliferative depsipeptide. It comes from the Leptolyngbya cyanobacterium.[1]
References
[edit]- ^ Medina, Rebecca A.; Goeger, Douglas E.; Hills, Patrice; Mooberry, Susan L.; Huang, Nelson; Romero, Luz I.; Ortega-Barría, Eduardo; Gerwick, William H.; McPhail, Kerry L. (2008). "Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamanian Marine Cyanobacterium Leptolyngbyasp". Journal of the American Chemical Society. 130 (20): 6324–5. doi:10.1021/ja801383f. PMC 2659736. PMID 18444611.