File:5tct LTag DNA.png

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Summary

Description
English: The hexameric assembly of the SV40 polyomavirus large tumor antigen (LTag) zinc finger and helicase domains (rainbow) bound to ADP (white spheres) and a double-helical DNA structure (center, light and dark gray) that forms the origin of replication in the viral genome.

Compare File:2h1l LTag p53.png, showing the same protein bound to cellular p53.

Rendered from PDB ID 5TCT: Elife. 2016 Dec 6;5. pii: e18129. doi: 10.7554/eLife.18129. The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA. Gai D, Wang D, Li SX, Chen XS. DOI: 10.7554/eLife.18129

PMID: 27921994
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Source Own work
Author Opabinia regalis

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17 February 2017

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current01:22, 18 February 2017Thumbnail for version as of 01:22, 18 February 20171,200 × 1,200 (1.1 MB)Opabinia regalis{{Information |Description ={{en|1=The hexameric assembly of the SV40 polyomavirus large tumor antigen (LTag) zinc finger and helicase domains (rainbow) bound to ADP (white spheres) and a double-helical DNA structure (center, light and dark gray) th...

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