File:DARTS.png

Original file (3,111 × 1,167 pixels, file size: 436 KB, MIME type: image/png)

Summary

Description
English: An example DARTS workflow. A lysate is split into control and drug treated groups. Lysates are exposed to limited proteolysis. Upon binding a drug, a protein is stabilized and protected from digestion. Undigested proteins can then be detected via western blot (for target validation) or their absence from digests can be measured via mass spectrometry (for target identification).
Date
Source Own work
Author Sgold626

Licensing

I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
attribution share alike
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.

Captions

DARTS: Drug Affinity Responsive Target Stability

Items portrayed in this file

depicts

7 December 2021

image/png

705a5bcb515b454796fa86113ac4d2912804741a

446,814 byte

1,167 pixel

3,111 pixel

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current21:58, 7 December 2021Thumbnail for version as of 21:58, 7 December 20213,111 × 1,167 (436 KB)Sgold626Uploaded own work with UploadWizard

The following 2 pages use this file:

Global file usage

The following other wikis use this file:

Metadata