File:ELMO1 (CED-12) and DOCK2 (CED-5) ternary complex in apoptosis.jpg

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English: (A) A simple graphical representation of the protein domains for DOCK2 (mammalian homolog to CED-5) and ELMO1 (mammalian homolog for CED-12). On DOCK2/CED-5, the SH3-domain that binds to ELMO1/CED-12 is shown as a blue rectangle. On ELMO1, Proline-Rich regions are in light-blue. These indicate the regions in which ELMO1/CED-12 and DOCK2/CED-5 interact when forming a complex. (B) A crystalline 3D-representation of the heterodimer structure between DOCK2/CED-5 and ELMO1/CED-12. On the right is the same crystalline structure rotated 90°.
Date
Source https://www.ncbi.nlm.nih.gov/pubmed/22331897
Author Kyoko Hanawa-Suetsugu, Mutsuko Kukimoto-Niino, Chiemi Mishima-Tsumagari, Ryogo Akasaka, Noboru Ohsawa, Shun-ichi Sekine, Takuhiro Ito, Naoya Tochio, Seizo Koshiba, Takanori Kigawa, Takaho Terada, Mikako Shirouzu, Akihiko Nishikimi, Takehito Uruno, Tomoya Katakai, Tatsuo Kinashi, Daisuke Kohda, Yoshinori Fukui, and Shigeyuki Yokoyamaa,

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13 February 2012

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