HSD17B11

HSD17B11
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHSD17B11, 17-BETA-HSD11, 17-BETA-HSDXI, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2, hydroxysteroid (17-beta) dehydrogenase 11, hydroxysteroid 17-beta dehydrogenase 11
External IDsOMIM: 612831; MGI: 2149821; HomoloGene: 69209; GeneCards: HSD17B11; OMA:HSD17B11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016245

NM_053262

RefSeq (protein)

NP_057329

NP_444492

Location (UCSC)Chr 4: 87.34 – 87.39 MbChr 5: 104.14 – 104.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Estradiol 17-beta-dehydrogenase 11 is an enzyme that in humans is encoded by the HSD17B11 gene.[5][6][7][8]

HSD17B11 expression has been linked to higher survival rates for lung cancer patients.[9]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198189Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029311Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Brereton P, Suzuki T, Sasano H, Li K, Duarte C, Obeyesekere V, Haeseleer F, Palczewski K, Smith I, Komesaroff P, Krozowski Z (January 2001). "Pan1b (17betaHSD11)-enzymatic activity and distribution in the lung". Molecular and Cellular Endocrinology. 171 (1–2): 111–7. doi:10.1016/S0303-7207(00)00417-2. PMID 11165019. S2CID 54263651.
  6. ^ Chai Z, Brereton P, Suzuki T, Sasano H, Obeyesekere V, Escher G, Saffery R, Fuller P, Enriquez C, Krozowski Z (May 2003). "17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells". Endocrinology. 144 (5): 2084–91. doi:10.1210/en.2002-221030. PMID 12697717.
  7. ^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jörnvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (March 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chemico-Biological Interactions. 178 (1–3): 94–8. Bibcode:2009CBI...178...94P. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
  8. ^ "Entrez Gene: HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11".
  9. ^ "Research update from the MCM team (March 2024)". World Community Grid. 14 March 2024. Retrieved 21 May 2024.

Further reading

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