LRP1B

LRP1B
Identifiers
AliasesLRP1B, LRP-DIT, LRPDIT, LDL receptor related protein 1B, LRP-1B
External IDsOMIM: 608766; MGI: 2151136; HomoloGene: 56810; GeneCards: LRP1B; OMA:LRP1B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018557

NM_053011

RefSeq (protein)

NP_061027

n/a

Location (UCSC)Chr 2: 140.23 – 142.13 MbChr 2: 40.49 – 42.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Low-density lipoprotein receptor-related protein 1B is a protein that in humans is encoded by the LRP1B gene.[5][6]

Function

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LRP1B belongs to the LDL receptor gene family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168702Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000049252Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Liu CX, Musco S, Lisitsina NM, Forgacs E, Minna JD, Lisitsyn NA (May 2000). "LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines". Cancer Res. 60 (7): 1961–7. PMID 10766186.
  6. ^ "Entrez Gene: LRP1B low density lipoprotein-related protein 1B (deleted in tumors)".
  7. ^ Liu CX, Li Y, Obermoeller-McCormick LM, Schwartz AL, Bu G (August 2001). "The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein". J. Biol. Chem. 276 (31): 28889–96. doi:10.1074/jbc.M102727200. PMID 11384978.

Further reading

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