List of adverse effects of lurasidone
This is a list of adverse effects of the antipsychotic drug lurasidone, sorted by frequency of occurrence.[1][2][3]
Very common
[edit]Very common (>10% incidence) adverse effects include:
- Somnolence† (produces an intermediate degree of sedation compared to other atypical antipsychotics[4])
- Akathisia†
- Fasting glucose increased†
- Nausea†
- Parkinsonism†
- Insomnia†
† These are dose-dependent.
Common
[edit]Common (1–10% incidence) adverse effects include:
- Vomiting†
- Dyspepsia†
- Agitation†
- Anxiety†
- Dystonia
- Dizziness†
- Fatigue
- Back pain†
- Restlessness
- Hypersalivation†
- Weight gain†[5]
† These are dose-dependent.
Uncommon
[edit]Uncommon (0.1–1% incidence) adverse effects include:
- Orthostatic hypotension
- Syncope
- Stroke
- Seizure
- Suicidal ideation
- Elevated serum creatinine
Rare
[edit]Rare (<0.01% incidence) adverse effects include:
Unknown frequency
[edit]Unknown frequency adverse effects include:
- Transient ischaemic attack
- Hyperprolactinaemia (seems to be a rather prominent adverse effect according to a meta-analysis[4])
- Hypothermia
References
[edit]- ^ Truven Health Analytics, Inc. DrugPoint System (Internet) [cited 2013 Oct 1]. Greenwood Village, CO: Thomsen Healthcare; 2013.
- ^ lurasidone (Rx) - Latuda [Internet]. Medscape Reference. [cited 2013 Oct 1]. Available from: http://reference.medscape.com/drug/latuda-lurasidone-999605#4
- ^ LATUDA (lurasidone hydrochloride) tablet, film coated [Bushu Pharmaceutical, LTD.] [Internet]. DailyMed. 2010 [cited 2013 Oct 1]. Available from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=88a244d1-eddb-499c-bee2-e1f49056e78f
- ^ a b Leucht, S; Cipriani, A; Spineli, L; Mavridis, D; Orey, D; Richter, F; Samara, M; Barbui, C; Engel, RR; Geddes, JR; Kissling, W; Stapf, MP; Lässig, B; Salanti, G; Davis, JM (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis". Lancet. 382 (9896): 951–962. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019. S2CID 32085212.
- ^ Ketter, T. A; Sarma, K; Silva, R; Kroger, H; Cucchiaro, J; Loebel, A (2016-02-26). "LURASIDONE IN THE LONG-TERM TREATMENT OF PATIENTS WITH BIPOLAR DISORDER: A 24-WEEK OPEN-LABEL EXTENSION STUDY". Depression and Anxiety. 33 (5): 424–434. doi:10.1002/da.22479. PMC 5069590. PMID 26918425.