List of cutaneous conditions associated with internal malignancy

See also: List of cutaneous conditions
This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources.

This is a list of cutaneous conditions associated with internal malignancy; skin markers of internal cancer.[1] It does not include skin infections associated with cancer or cancers that spread to skin.[1] Some have stronger associations with cancers than others.[2]

Cutaneous conditions associated with internal benign tumors and/or malignancies
Cutaneous condition Internal malignancy
Erythema gyratum repens Lung cancer
Hypertrichosis lanuginosa acquisita Lung cancer
Paraneoplastic pemphigus Non-Hodgkin lymphoma[nb 1]
Chronic lymphocytic leukemia
Castleman's disease[nb 1]
Sarcoma
Thymoma
Tripe palms Lung cancer
Tripe palms with acanthosis nigricans Stomach cancer
Pityriasis rotunda Hepatocellular carcinoma
Migratory thrombophlebitis Pancreatic adenocarcinoma
Leser–Trélat sign Gastrointestinal adenocarcinoma
Acquired ichthyosis Hodgkin disease
Pityriasis rotunda Hepatocellular carcinoma
Paraneoplastic pigmentation Small cell bronchial carcinoma
Acrokeratosis paraneoplastica Squamous cell carcinoma of the upper respiratory or gastrointestinal

tracts

Necrolytic migratory erythema Glucagon secreting

pancreatic islet cell adenoma

Dermatomyositis Lung cancer in men, breast and gynaecological tumours in women and colorectal cancers in both sexes
Scleroderma‐like skin changes Carcinoid syndrome
Paraneoplastic pemphigus B‐cell proliferations and thymoma or thymoma‐like neoplasms; specifically Non Hodgkin's lymphoma (42%)
Dermatitis herpetiformis Lymphoma
Porphyria cutanea tarda and variegate porphyrias Hepatocellular Carcinoma
Erythroderma and exfoliative dermatitis Mycosis fungoides or Sézary syndrome
Pyoderma gangrenosum Hematological malignancy
Sweet syndrome Hematological malignancy

Footnotes

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  1. ^ a b Non-Hodgkin lymphoma is the most common cause of paraneoplastic pemphigus in adults. Castleman's disease is the most common cause of paraneoplastic pemphigus in children.

See also

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References

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  1. ^ a b Wick, Mark R.; Patterson, James W. (July 2019). "Cutaneous paraneoplastic syndromes". Seminars in Diagnostic Pathology. 36 (4): 211–228. doi:10.1053/j.semdp.2019.01.001. ISSN 0740-2570. PMID 30736994.
  2. ^ Fonia, Athina; Baran, Robert (2021). "Cutaneous paraneoplastic syndromes with nail involvement". In Lipner, Shari (ed.). Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics. Elsevier. pp. 175–182. ISBN 978-0-323-70924-8.

Bibliography

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  • Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 1-4160-2999-0.
  • James, William D.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
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