Human enzyme
E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene .[ 5] apoptosis .[ 6]
Confusion with proliferative marker [ edit ] An antibody directed at the protein Ki-67 , a product of the MKI67 gene , is called MIB-1 .[ 7]
Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 7 (1): 65–73. doi :10.1093/dnares/7.1.65 PMID 10718198 . Wang Z, Tseng CP, Pong RC, et al. (2002). "The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2" . J. Biol. Chem . 277 (15): 12622–31. doi :10.1074/jbc.M110568200 PMID 11812785 . Jin Y, Blue EK, Dixon S, et al. (2003). "A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK" . J. Biol. Chem . 277 (49): 46980–6. doi :10.1074/jbc.M208585200 PMC 2824503 PMID 12351649 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Itoh M, Kim CH, Palardy G, et al. (2003). "Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta" . Dev. Cell . 4 (1): 67–82. doi :10.1016/S1534-5807(02)00409-4 PMID 12530964 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Henshall DC, Schindler CK, So NK, et al. (2004). "Death-associated protein kinase expression in human temporal lobe epilepsy". Ann. Neurol . 55 (4): 485–94. doi :10.1002/ana.20001 . PMID 15048887 . S2CID 35261517 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Yoo KW, Kim EH, Jung SH, et al. (2006). "Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish". FEBS Lett . 580 (18): 4409–16. doi :10.1016/j.febslet.2006.07.009 . PMID 16857196 . S2CID 37762815 . Song R, Koo BK, Yoon KJ, et al. (2007). "Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1" . J. Biol. Chem . 281 (47): 36391–400. doi :10.1074/jbc.M606601200 PMID 17003037 . Zhang L, Nephew KP, Gallagher PJ (2007). "Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexes" . J. Biol. Chem . 282 (16): 11795–804. doi :10.1074/jbc.M610430200 PMC 2823631 PMID 17324930 . Yakut T, Gutenberg A, Bekar A, et al. (2007). "Correlation of chromosomal imbalances by comparative genomic hybridization and expression of EGFR, PTEN, p53, and MIB-1 in diffuse gliomas" . Oncol. Rep . 17 (5): 1037–43. doi :10.3892/or.17.5.1037 PMID 17390041 . van der Avoort IA, van der Laak JA, Paffen A, et al. (2007). "MIB1 expression in basal cell layer: a diagnostic tool to identify premalignancies of the vulva" . Mod. Pathol . 20 (7): 770–8. doi :10.1038/modpathol.3800796 hdl :2066/51438 PMID 17464313 .
French
Deutsch
