RNF146

RNF146
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D8T, 3V3L
Identifiers
Aliases	RNF146, dJ351K20.1, ring finger protein 146
External IDs	OMIM: 612137; MGI: 1915281; HomoloGene: 12227; GeneCards: RNF146; OMA:RNF146 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	127,288,567 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	29,238,438 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; Skeletal muscle tissue of rectus abdominis; ; gastric mucosa; ; tibia; ; biceps brachii; ; middle temporal gyrus; ; tendon; ; body of uterus;
	Top expressed in
	interventricular septum; ; motor neuron; ; Region I of hippocampus proper; ; cumulus cell; ; superior cervical ganglion; ; vestibular sensory epithelium; ; primitive streak; ; trigeminal ganglion; ; vestibular membrane of cochlear duct; ; medial ganglionic eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; protein binding; metal ion binding; ubiquitin-protein transferase activity; poly-ADP-D-ribose binding; ubiquitin protein ligase activity; transferase activity;
Cellular component	cytoplasm; cytosol; nucleus; nucleoplasm; plasma membrane;
Biological process	positive regulation of canonical Wnt signaling pathway; protein K48-linked ubiquitination; protein ubiquitination; protein autoubiquitination; ubiquitin-dependent protein catabolic process; Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	81847
	68031
	ENSG00000118518
	ENSMUSG00000038876
	Q9NTX7
	Q9CZW6
NM_001242844; NM_001242845; NM_001242846; NM_001242847; NM_001242848;
	NM_001242849; NM_001242850; NM_001242851; NM_001242852; NM_030963
	NM_001110196; NM_001110197; NM_001110198; NM_001284279; NM_026518
NP_001229773; NP_001229774; NP_001229775; NP_001229776; NP_001229777;
	NP_001229778; NP_001229779; NP_001229780; NP_001229781; NP_112225
	NP_001103666; NP_001103667; NP_001103668; NP_001271208; NP_080794
	Wikidata
View/Edit Human	View/Edit Mouse

RING finger protein 146 is a protein that in humans is encoded by the RNF146 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000118518 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038876 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: RNF146 ring finger protein 146".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
von Rotz RC, Kins S, Hipfel R, et al. (2005). "The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease". Eur. J. Neurosci. 21 (5): 1289–98. doi:10.1111/j.1460-9568.2005.03977.x. PMID 15813938. S2CID 2715969.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000118518 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038876 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: RNF146 ring finger protein 146".

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RNF146

References

Further reading