Ro 3-0412
Names | |
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Preferred IUPAC name 3-[(Dimethoxyphosphoryl)oxy]-N,N,N-trimethylanilinium methyl sulfate | |
Other names Dimethylphosphostigmine | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
PubChem CID | |
CompTox Dashboard (EPA) | |
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Properties | |
C12H22NO8PS | |
Molar mass | 371.34 g·mol−1 |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | 0.57 mg/kg (mice, intravenous) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Ro 3-0412 is an acetylcholinesterase inhibitor. It is the organophosphate analog of neostigmine.[1]
See also
[edit]References
[edit]- ^ BURGEN, AS; HOBBIGER, F (December 1951). "The inhibition of cholinesterases by alkyl-phosphates and alkylphenolphosphates". British Journal of Pharmacology and Chemotherapy. 6 (4): 593–605. doi:10.1111/j.1476-5381.1951.tb00670.x. PMC 1509150. PMID 14904884.