S-14,506
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Names | |
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Preferred IUPAC name 4-Fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide | |
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Properties | |
C24H26FN3O2 | |
Molar mass | 407.489 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
S-14,506 is a naphthylpiperazine, a 5-HT1A receptor agonist,[1] and a dopamine receptor antagonist.[2]
References
[edit]- ^ Milligan, G.; Kellett, E.; Dacquet, C.; Dubreuil, V.; Jacoby, E.; Millan, M. J.; Lavielle, G.; Spedding, M. (2001). "S 14506: Novel receptor coupling at 5-HT(1A) receptors". Neuropharmacology. 40 (3): 334–344. doi:10.1016/s0028-3908(00)00162-3. PMID 11166326. S2CID 36060096.
- ^ Protais, P.; Chagraoui, A.; Arbaoui, J.; Mocaër, E. (1994). "Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents". European Journal of Pharmacology. 271 (1): 167–177. doi:10.1016/0014-2999(94)90277-1. PMID 7698199.