SULT2B1

SULT2B1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSULT2B1, HSST2, sulfotransferase family 2B member 1, ARCI14
External IDsOMIM: 604125; MGI: 1926342; HomoloGene: 49487; GeneCards: SULT2B1; OMA:SULT2B1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004605
NM_177973

NM_017465
NM_001360784

RefSeq (protein)

NP_004596
NP_814444

NP_059493
NP_001347713

Location (UCSC)Chr 19: 48.55 – 48.6 MbChr 7: 45.38 – 45.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sulfotransferase family cytosolic 2B member 1 is an enzyme that in humans is encoded by the SULT2B1 gene.[5][6]

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic chemical compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described.[6]

See also

[edit]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000088002Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003271Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Her C, Wood TC, Eichler EE, Mohrenweiser HW, Ramagli LS, Siciliano MJ, Weinshilboum RM (Dec 1998). "Human hydroxysteroid sulfotransferase SULT2B1: two enzymes encoded by a single chromosome 19 gene". Genomics. 53 (3): 284–95. doi:10.1006/geno.1998.5518. PMID 9799594.
  6. ^ a b "Entrez Gene: SULT2B1 sulfotransferase family, cytosolic, 2B, member 1".

Further reading

[edit]