Protein-coding gene in the species Homo sapiens
ZDHHC8 is a putative palmitoyltransferase enzyme containing a DHHC domain that in humans is encoded by the ZDHHC8 gene .[ 4] [ 5] [ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000099904 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (Jan 2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 6 (5): 337–45. doi :10.1093/dnares/6.5.337 PMID 10574462 . ^ Mukai J, Liu H, Burt RA, Swor DE, Lai WS, Karayiorgou M, Gogos JA (Jun 2004). "Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia" . Nat Genet . 36 (7): 725–31. doi :10.1038/ng1375 PMID 15184899 . ^ "Entrez Gene: ZDHHC8 zinc finger, DHHC-type containing 8" . Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22" . Nature . 402 (6761): 489–95. Bibcode :1999Natur.402..489D . doi :10.1038/990031 PMID 10591208 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome" . Genome Biol . 5 (10): R84. doi :10.1186/gb-2004-5-10-r84 PMC 545604 PMID 15461802 . Chen WY, Shi YY, Zheng YL, et al. (2005). "Case-control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8" . Hum. Mol. Genet . 13 (23): 2991–5. doi :10.1093/hmg/ddh322 PMID 15489219 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Saito S, Ikeda M, Iwata N, et al. (2005). "No association was found between a functional SNP in ZDHHC8 and schizophrenia in a Japanese case-control population". Neurosci. Lett . 374 (1): 21–4. doi :10.1016/j.neulet.2004.10.015 . PMID 15631889 . S2CID 24312967 . Glaser B, Schumacher J, Williams HJ, et al. (2005). "No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples". Biol. Psychiatry . 58 (1): 78–80. doi :10.1016/j.biopsych.2005.03.017 . PMID 15992527 . S2CID 20264569 . Otani K, Ujike H, Tanaka Y, et al. (2006). "The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia". Neurosci. Lett . 390 (3): 166–70. doi :10.1016/j.neulet.2005.08.019 . PMID 16150541 . S2CID 26919027 . Demily C, Legallic S, Bou J, et al. (2007). "ZDHHC8 single nucleotide polymorphism rs175174 is not associated with psychiatric features of the 22q11 deletion syndrome or schizophrenia". Psychiatr. Genet . 17 (5): 311–2. doi :10.1097/YPG.0b013e328133f369 . PMID 17728672 .
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