Posizione | Batteria | Corsia | Atleta | Nazionalità | Tempo | Note |
1 | 6 | 4 | Dressel, Caeleb Caeleb Dressel | Stati Uniti | 50"08 | Q |
2 | 6 | 3 | Codia, Piero Piero Codia | Italia | 51"09 | Q |
3 | 7 | 6 | Guy, James James Guy | Gran Bretagna | 51"16 | Q |
4 | 8 | 4 | Schooling, Joseph Joseph Schooling | Singapore | 51"21 | Q |
5 | 8 | 6 | Milák, Kristóf Kristóf Milák | Ungheria | 51"23 | Q, MJ |
6 | 8 | 5 | le Clos, Chad Chad le Clos | Sudafrica | 51"28 | Q |
7 | 7 | 3 | Metella, Mehdy Mehdy Metella | Francia | 51"46 | Q |
8 | 6 | 6 | Martins, Henrique Henrique Martins | Brasile | 51"48 | Q |
9 | 7 | 5 | Czerniak, Konrad Konrad Czerniak | Polonia | 51"50 | Q |
10 | 7 | 4 | Cseh, László László Cseh | Ungheria | 51"55 | Q |
11 | 6 | 5 | Li Zhuhao | Cina | 51"62 | Q |
12 | 7 | 2 | Irvine, Grant Grant Irvine | Australia | 51"67 | Q |
13 | 6 | 7 | Świtkowski, Jan Jan Świtkowski | Polonia | 51"82 | Q |
14 | 8 | 8 | Popkov, Aleksandr Aleksandr Popkov | Russia | 51"84 | Q |
15 | 8 | 2 | Morgan, David David Morgan | Australia | 51"90 | Q |
16 | 8 | 3 | Phillips, Tim Tim Phillips | Stati Uniti | 51"96 | Q |
17 | 7 | 0 | Goosen, Mathys Mathys Goosen | Paesi Bassi | 52"12 | |
18 | 8 | 1 | Quah Zheng Wen | Singapore | 52"13 | |
19 | 5 | 6 | Sabo, Sebastian Sebastian Sabo | Serbia | 52"16 | |
20 | 7 | 7 | Kobori, Yuki Yuki Kobori | Giappone | 52"17 | |
21 | 7 | 8 | Martínez, Luis Luis Martínez | Guatemala | 52"18 | |
22 | 6 | 2 | Kusch, Marius Marius Kusch | Germania | 52"22 | |
23 | 7 | 1 | Pakhomov, Daniil Daniil Pakhomov | Russia | 52"47 | |
24 | 4 | 1 | Ayar, Kaan Kaan Ayar | Turchia | 52"52 | |
25 | 6 | 1 | Grassi, Santiago Santiago Grassi | Argentina | 52"59 | |
26 | 5 | 2 | Šefl, Jan Jan Šefl | Rep. Ceca | 52"65 | |
27 | 5 | 0 | Croenen, Louis Louis Croenen | Belgio | 52"74 | |
28 | 7 | 9 | Carter, Dylan Dylan Carter | Trinidad e Tobago | 52"75 | |
29 | 8 | 7 | Sankovič, Pavel Pavel Sankovič | Bielorussia | 52"87 | |
30 | 6 | 9 | Vazaios, Andreas Andreas Vazaios | Grecia | 52"88 | |
31 | 4 | 2 | Kozlyuk, Artyom Artyom Kozlyuk | Uzbekistan | 52"95 | |
32 | 6 | 8 | Lemeshko, Liubomyr Liubomyr Lemeshko | Ucraina | 52"97 | |
33 | 6 | 0 | Bromer, Viktor Viktor Bromer | Danimarca | 53"01 | |
34 | 5 | 3 | Binnema, Josiah Josiah Binnema | Canada | 53"10 | |
35 | 8 | 0 | Carini, Giacomo Giacomo Carini | Italia | 53"13 | |
36 | 8 | 9 | Schlesinger, Marcus Marcus Schlesinger | Israele | 53"20 | |
37 | 4 | 4 | Mussin, Adilbek Adilbek Mussin | Kazakistan | 53"37 | |
38 | 4 | 3 | Liess, Nils Nils Liess | Svizzera | 53"50 | |
39 | 4 | 7 | Hockin, Ben Ben Hockin | Paraguay | 53"51 | |
40 | 4 | 0 | Pöytäkivi, Riku Riku Pöytäkivi | Finlandia | 53"62 | |
41 | 5 | 1 | Ivanov, Antani Antani Ivanov | Bulgaria | 53"66 | |
41 | 5 | 4 | Sidiq, Triady Fauzi Triady Fauzi Sidiq | Indonesia | 53"66 | |
43 | 5 | 5 | Zirk, Kregor Kregor Zirk | Estonia | 53"70 | |
44 | 5 | 9 | Hyland, Brendan Brendan Hyland | Irlanda | 53"80 | |
45 | 4 | 8 | Lavado, Marcos Marcos Lavado | Venezuela | 53"97 | |
45 | 5 | 7 | Duškinas, Tadas Tadas Duškinas | Lituania | 53"97 | |
47 | 3 | 2 | Chou Wei-liang | Taipei cinese | 54"31 | |
48 | 3 | 3 | Prakash , Sajan Sajan Prakash | India | 54"46 | |
49 | 3 | 4 | Arias, David David Arias | Colombia | 54"48 | |
50 | 4 | 9 | Martínez, José José Martínez | Messico | 54"50 | |
51 | 5 | 8 | Eissa, Omar Omar Eissa | Egitto | 54"59 | |
52 | 4 | 5 | Hoàng Quý Phước | Vietnam | 54"76 | |
53 | 3 | 5 | Goveia, Ralph Ralph Goveia | Zambia | 54"86 | |
54 | 3 | 7 | Sperandio Sánchez, Christian Christian Sperandio Sánchez | Rep. Dominicana | 54"98 | |
55 | 3 | 6 | de Silva, Cherantha Cherantha de Silva | Sri Lanka | 55"09 | |
56 | 3 | 0 | Ansari, Mehdi Mehdi Ansari | Iran | 55"31 | |
57 | 2 | 4 | Umnov, Mikhail Mikhail Umnov | Malta | 55"58 | |
58 | 3 | 9 | Anis, Rami Rami Anis | Atleti indipendenti FINA | 55"66 | |
59 | 3 | 8 | Alvarez, Bryan Bryan Alvarez | Costa Rica | 55"85 | |
60 | 3 | 1 | Kelzi, Ayman Ayman Kelzi | Siria | 56"59 | |
61 | 2 | 3 | Soammanus, Jeerakit Jeerakit Soammanus | Thailandia | 56"88 | |
62 | 2 | 5 | Toure, Oumar Oumar Toure | Mali | 57"52 | |
63 | 2 | 1 | Nmor, Ifeakachuku Ifeakachuku Nmor | Nigeria | 57"90 | |
64 | 1 | 3 | Al-Doori, Abdullah Abdullah Al-Doori | Iraq | 58"01 | |
65 | 2 | 2 | Jabbour, George George Jabbour | Honduras | 58"29 | |
66 | 1 | 5 | Al-Khulaifi, Yacob Yacob Al-Khulaifi | Qatar | 58"42 | |
67 | 2 | 6 | Gaskin, Hannibal Hannibal Gaskin | Guyana | 58"69 | |
68 | 1 | 4 | Francisco, Daniel Daniel Francisco | Angola | 58"79 | |
69 | 1 | 6 | Poppe, Tanner Tanner Poppe | Guam | 1'03"28 | |
70 | 2 | 9 | Dlamini, Simanga Simanga Dlamini | eSwatini | 1'04"02 | |
71 | 2 | 7 | Roberto, David David Roberto | Isole Marianne Settentrionali | 1'06"80 | |
72 | 2 | 0 | Gooding, Dillon Dillon Gooding | Saint Vincent e Grenadine | 1'07"11 | |
- | 4 | 6 | Perry, Sam Sam Perry | Nuova Zelanda | - | DNS |