Het wereldkampioenschap superbike seizoen 2000 was het 13e in de geschiedenis van het door de FIM georganiseerde wereldkampioenschap superbike. Het seizoen telde dertien wedstrijden die telkens door middel van twee races werden verreden. Het seizoen begon op 2 april op het Circuit Kyalami in Zuid-Afrika en eindigde op 15 oktober op Brands Hatch in het Verenigd Koninkrijk. De Amerikaan Colin Edwards wist het kampioenschap te winnen met 400 punten.
| Team | Constructeur | Motor | Nr. | Coureur | Races | | Ducati Infostrada | Ducati | Ducati 996 | 1 |  Carl Fogarty | 1–2 | | 19 |  Juan Borja | 6–13 | | 21 |  Troy Bayliss | 3, 5–13 | | 22 |  Luca Cadalora | 4 | | 155 |  Ben Bostrom | 1–5 | | Castrol Honda | Honda | Honda VTR1000 | 2 | Colin Edwards | Alle | | 5 |  Simon Crafar | 1–2 | | 36 |  Manabu Kamada | 3 | | 111 | Aaron Slight | 4–13 | | Aprilia Racing | Aprilia | Aprilia RSV 1000 | 3 | Troy Corser | Alle | | 30 | Alessandro Antonello | 1, 4–8, 10–13 | | Kawasaki Racing | Kawasaki | Kawasaki ZX-7RR | 4 | Akira Yanagawa | Alle | | 5 | Simon Crafar | 6 | | 6 | Gregorio Lavilla | 1–5, 10–13 | | 14 | Peter Goddard | 7–9 | | 14 | Peter Goddard | 12 | | 62 | Tamaki Serizawa | 3 | | 64 | Hitoyasu Izutsu | 3 | | Suzuki Alstare | Suzuki | Suzuki GSX-R750 | 7 | Pierfrancesco Chili | Alle | | 9 | Katsuaki Fujiwara | Alle | | Yamaha WSBK | Yamaha | Yamaha YZF-R7 | 10 | Vittoriano Guareschi | Alle | | 41 | Noriyuki Haga | 1–12 | | 57 | Wataru Yoshikawa | 3, 12 | | Pedercini | Ducati | Ducati RS 996 | 11 | Lucio Pedercini | 2–13 | | 20 | Marco Borciani | 1–7, 9–13 | | 31 | Marco Gerbaudo | 8 | | 46 | Mauro Sanchini | Alle | | R & D Bieffe | Ducati | Ducati RS 996 | 12 | Haruchika Aoki | 1–5, 7–10 | | 82 | Doriano Romboni | 11–12 | | Gerin WSBK | Ducati | Ducati 996 RS2000 | 13 |  Andreas Meklau | Alle | | 33 | Robert Ulm | Alle | | Kawasaki Bertocchi | Kawasaki | Kawasaki ZX-7RR | 15 | Igor Antonelli | 1–8 | | 32 | Massimo De Silvestro | 1, 4–8, 10–13 | | 35 | Giovanni Bussei | Alle | | 76 |  Igor Jerman | 9–13 | | Alpha Technik Yamaha | Yamaha | Yamaha R7 | 18 |  Markus Barth | 4–8, 10–13 | | 28 | Jürgen Oelschläger | 4–8, 10–13 | | Ducati NCR | Ducati | Ducati RS 996 | 19 | Juan Borja | 1–5 | | 38 |  Lance Isaacs | Alle | | 155 | Ben Bostrom | 6–13 | | JM SBK | Ducati | Ducati 996R | 23 |  Jiří Mrkývka | 1–3, 5–8, 10–13 | | Karban Racing | Suzuki | Suzuki GSX-R750 | 24 |  Vladimír Karban | 1–2, 4–6 | | FP Racing | Ducati | Ducati | 27 |  Frédéric Protat | 5, 7–8, 10 | | 68 | Thierry Mulot | 7–8 | | Valli Racing 391 | Yamaha | Yamaha R7 | 39 | Alessandro Gramigni | 1, 4–8, 10–13 | | Kawasaki UK | Kawasaki | Kawasaki ZX-7RR | 40 | Steve Plater | 6, 13 | | National Tyres Clar. | Suzuki | Suzuki GSX-R750 | 42 | John Crawford | 4 | | 49 | Chris Walker | 4, 10, 13 | | Virgin Mobile Yamaha | Yamaha | Yamaha | 43 | Steve Hislop | 4, 10 | | 501 | Anthony Gobert | 13 | | Philippe Coulon | Honda | Honda VTR1000 | 44 |  Claude-Alain Jäggi | 2–6, 8, 10 | | 83 | Gerald Muteau | 11–13 | | Reve Red Bull | Ducati | Ducati RS 996 | 45 | James Haydon | 4, 6, 10, 13 | | 47 | John Reynolds | 4, 6, 10, 13 | | INS - GSE Racing | Ducati | Ducati | 48 | Neil Hodgson | 4, 10, 13 | | SRT Shell Kawasaki | Kawasaki | Kawasaki ZX-7RR | 50 | Alistair Maxwell | 2 | | Stevens Motorcycles | Suzuki | Suzuki GSX-R750 | 51 | David Simpson | 2 | | Warrea & Brown L. | Suzuki | Suzuki GSX-R750 | 52 | Jay Normoyle | 2 | | Sean McKay Racing | Kawasaki | Kawasaki ZX-7RR | 53 | Sean McKay | 2 | | Steven R. Monza Imp. | Kawasaki | Kawasaki ZX-7RR | 54 | Greg Smith | 2 | | Ferrari Dental Cl. | Ducati | Ducati | 55 | Mark Ferrari | 2 | | Webster | Honda | Honda VTR1000 | 56 | Scott Webster | 2 | | Suzuki | Suzuki | Suzuki GSX-R750 | 58 | Akira Ryo | 3 | | 59 | Keiichi Kitagawa | 3 | | Cabin Honda | Honda | Honda VTR1000 | 60 | Shinichi Ito | 3 | | Kotake RSC | Honda | Honda RC45 | 61 | Makoto Tamada | 3 | | Sakurai Honda | Honda | Honda VTR1000 | 63 | Yuichi Takeda | 3 | | Pacific | Ducati | Ducati 996 RS2000 | 65 | Giuliano Sartoni | 7–8, 12 | | 91 | Daniele Morigi | 10–12 | | 113 | Paolo Blora | 4–9 | | Kawasaki France | Kawasaki | Kawasaki ZX-7RR | 67 | Ludovic Holon | 7 | | White Endurance | Honda | Honda VTR1000 | 69 | Jonnie Ekerold | 1–7 | | 78 | Bertrand Stey | 10–13 | | 80 | José Oriol Fernández | 8 | | Ghelfi Art Racing | Honda | Honda VTR1000 | 70 | Javier Rodríguez | 8, 11–13 | | Procurde RPM Expert | Ducati | Ducati 996 SPS | 71 | Guim Roda | 8 | | Pirelli Moto 2000 | Yamaha | Yamaha | 72 | Redamo Assirelli | 7 | | Comp. Acc. Ducati | Ducati | Ducati | 73 | Larry Pegram | 9 | | Pro Honda Oils Chem. | Honda | Honda | 74 | Brian Parriott | 9 | | Duyzers | Suzuki | Suzuki | 77 |  Maarten Duyzers | 11 | | Image Trading S100 | Suzuki | Suzuki | 79 | Robert van der Molen | 11 | | Hans v Wijk Motoren | Suzuki | Suzuki | 81 | Andre Coers | 11 | | Yamaha Denmark | Yamaha | Yamaha | 84 |  Rene Prang | 12 | | Yamaha Norway | Yamaha | Yamaha | 85 |  Oddgeir Havnen | 12 | | MVR Bimota Exp. | Bimota | Bimota SB8R | 501 | Anthony Gobert | 1–3, 5–6 | | |
| | | Kleur | Resultaat | | Goud | Winnaar | | Zilver | 2e plaats | | Brons | 3e plaats | | Groen | Gefinisht, in de punten | | Blauw | Gefinisht, geen punten | | Niet geclassificeerd (NC) | | Paars | Niet gefinisht (DNF) | | Rood | Niet gekwalificeerd (DNQ) | | Niet voorgekwalificeerd (DNPQ) | | Zwart | Gediskwalificeerd (DSQ) | | Wit | Niet gestart (DNS) | | Teruggetrokken (WD) | | Race geannuleerd (C) | | Leeg | Niet deelgenomen | | Uitgesloten (EX) | Vet – Pole position
Schuin – Snelste ronde |
| Pos | Constructeur | KYA
| PHI
| SUG
| DON
| MON
| HOC
| MIS
 | VAL
| LAG
| BRH
 | ASS
| OSC
| BRH
| Ptn |
| R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 | R1 | R2 |
| 1 | Ducati | 3 | 4 | 2 | 10 | 11 | 11 | 3 | 1 | 4 | 4 | 1 | 4 | 2 | 2 | 2 | 2 | 4 | 3 | 1 | 1 | 2 | 3 | 3 | 2 | 1 | 4 | 439 |
| 2 | Honda | 1 | 1 | 5 | 5 | 5 | 3 | 1 | 7 | 2 | 1 | 4 | 2 | 18 | 9 | 5 | 4 | 2 | 4 | 7 | 6 | 1 | 4 | 1 | 1 | 8 | 1 | 415 |
| 3 | Yamaha | 2 | 14 | 3 | 2 | 2 | 2 | 4 | 4 | 12 | 5 | 3 | 1 | 7 | 15 | 3 | 1 | 1 | 2 | 5 | 4 | 3 | 1 | 9 | 5 | 12 | 11 | 368 |
| 4 | Suzuki | 5 | 2 | 13 | 3 | 3 | 8 | 2 | 2 | 1 | 2 | 18 | 3 | 3 | 4 | 8 | 9 | 5 | 6 | 3 | 3 | 10 | 8 | 6 | 6 | 3 | 2 | 342 |
| 5 | Kawasaki | 6 | 5 | 7 | 4 | 1 | 1 | 7 | 5 | 3 | 3 | 2 | 14 | 5 | 6 | 6 | 6 | 6 | 5 | 9 | 5 | 6 | 2 | 2 | 3 | 6 | 5 | 334 |
| 6 | Aprilia | 4 | 3 | DNF | 1 | 9 | 5 | 8 | 11 | 8 | 6 | 7 | 6 | 1 | 1 | 1 | 5 | 3 | 1 | 6 | DNF | 4 | 7 | 7 | DNF | 7 | 3 | 315 |
| 7 | Bimota | DNF | 11 | 1 | 9 | DNF | DNF | | | 22 | DNF | DNF | DNF | | | | | | | | | | | | | | | 37 |
| Pos | Constructeur | KYA
| PHI
| SUG
| DON
| MON
| HOC
| MIS
| VAL
| LAG
| BRH
| ASS
| OSC
| BRH
| Ptn |
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