Pellagra - Simple English Wikipedia, the free encyclopedia
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Pellagra is a disease caused by a lack of niacin (vitamin B3). Niacin is found in most foods. A person can die from pellagra if it is not treated. The main results of pellagra can be remembered as "the three D's": diarrhea, dermatitis, dementia, and sometimes a fourth D, which is death.
Some symptoms of pellagra according to a few sources[verification needed] are:
- abdominal cramping
- depression
- diarrhea
- headache
- loss of appetite
- mucus membrane inflammation
- dilated cardiomyopathy
It may also cause a copper-colored 'necklace', or 'gauntlet' called the cascals necklace and gauntlet of pellagra to show[verification needed].
It is also caused due to cellular deficiency of a vitamin called niacin or sometimes nicotinic acid. Other causes are chronic alcoholism and gastro-intestinal malabsorption. It can be prevented by adequate intake of niacin or foods rich in vitamin B3 and dietary advice to vulnerable groups.
It is endemic in China and Africa[verification needed].
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