| 合胞素-1 |
|---|
|
| 識別號 |
|---|
| 别名 | ERVW-1；, ENV, ENVW, ERVWE1, HERV-7q, HERV-W-ENV, HERV7Q, HERVW, HERVWENV, endogenous retrovirus group W member 1, endogenous retrovirus group W member 1, envelope |
|---|
| 外部ID | OMIM：604659 HomoloGene：137309 GeneCards：ERVW-1 |
|---|
|
| 直系同源 |
|---|
| 物種 | 人類 | 小鼠 |
|---|
| Entrez | | |
|---|
| Ensembl | | |
|---|
| UniProt | | |
|---|
| mRNA序列 | | |
|---|
| 蛋白序列 | | |
|---|
| 基因位置（UCSC） | Chr 7: 92.47 – 92.48 Mb | 无数据 |
|---|
| PubMed查找 | [2] | 无数据 |
|---|
| 維基數據 |
|
合胞素-1（Syncytin-1，enverin）是一种在人类和其他灵长类动物中发现的蛋白质，它由ERVW-1基因编码。 該基因是一种内源性病毒元件，它是2500万年前逆转录病毒感染人類後的残余物[3]。合胞素有助於胎盘发育[4][5][6]。
- ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000242950 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Phylogeny of a novel family of human endogenous retrovirus sequences, HERV-W, in humans and other primates. AIDS Research and Human Retroviruses. November 1999, 15 (17): 1529–33. PMID 10580403. doi:10.1089/088922299309810.
- ^ From ancestral infectious retroviruses to bona fide cellular genes: role of the captured syncytins in placentation. Placenta. September 2012, 33 (9): 663–71. PMID 22695103. doi:10.1016/j.placenta.2012.05.005.
- ^ The role of syncytins in human reproduction and reproductive organ cancers. Reproduction (Cambridge, England). 2016, 152 (5): R167–78. PMID 27486264. doi:10.1530/REP-16-0031.
- ^ Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. September 2013, 368 (1626): 20120507. PMC 3758191
. PMID 23938756. doi:10.1098/rstb.2012.0507.
French
Deutsch
