四氢噻喃是化学式 C5H10S的杂环化合物。
四氢噻喃可以由1,5-二溴戊烷和硫化钠反应而成:[5]
![{\displaystyle \mathrm {C_{5}H_{10}S+2\ NaBr} }](https://wikimedia.org/api/rest_v1/media/math/render/svg/3b4a0237d76ae313443d43b422a390b8b8ff3f29)
它也可以由5-溴-1-戊硫醇和氢化钠反应而成:[6]
![{\displaystyle \mathrm {C_{5}H_{10}S+NaBr+H_{2}\ } }](https://wikimedia.org/api/rest_v1/media/math/render/svg/c23a6a8a54f172d4dd925ae62c0c04f1f2031d33)
1,5-二氯戊烷和硫化钠的反应也能得到四氢噻喃。[7]
四氢噻喃和溴乙酸反应,生成锍盐:[8]
- ^ G. H. Jeffery, R. Parker, A. I. Vogel in: J. Chem. Soc. 1961, 570–574.
- ^ D. Vedal, O. H. Ellestad, P. Klaboe, G. Hagen in: Spectrochim. Acta Part A 1975, 31, 355–372.
- ^ R. L. Crumbie, D. D. Ridley in: Aust. J. Chem. 1979, 32, 2777–2781.
- ^ S. Kondo in: Bull. Chem. Soc. Jpn. 1956, 29, 999.
- ^ NAGASAWA, KAZUO; YONETA, AKEMI. Organosulfur chemistry. II. Use of dimethyl sulfoxide; A facile synthesis of cyclic sulfides.. Chemical and Pharmaceutical Bulletin (Pharmaceutical Society of Japan). 1985, 33 (11): 5048–5052. ISSN 0009-2363. doi:10.1248/cpb.33.5048.
- ^ Anderson, M. B.; Ranasinghe, M. G.; Palmer, J. T.; Fuchs, P. L. Cytochalasin support studies. 10. Nucleophilic and electrophilic mercaptanylations via 2-(trimethylsilyl)ethanethiol-derived reagents. The Journal of Organic Chemistry (American Chemical Society (ACS)). 1988, 53 (13): 3125–3127. ISSN 0022-3263. doi:10.1021/jo00248a045.
- ^ Datenblatt 1,5-Dichloropentane, 98% bei AlfaAesar, abgerufen am {{{Abruf}}}.
- ^ E. Ziegler, H. Wittmann, H. Sterk in: Monatsh. Chem. 1987, 118, 115–126.