达西珠单抗 - 维基百科,自由的百科全书

达西珠单抗
单克隆抗体
种类完整抗体
目標CD40
臨床資料
其他名稱SGN-40
ATC碼
  • 未分配
识别信息
CAS号880486-59-9  checkY
ChemSpider
  • none
UNII
化学信息
化学式C6452H9964N1732O1998S42
摩尔质量145,111.33 g·mol−1

达西珠单抗INN:dacetuzumab;开发代号:SGN-40huS2C6)是一种人源化单克隆抗体[1]正在开发用于治疗CD40阳性癌症,如非霍奇金淋巴瘤[2]血液恶性肿瘤[3]

该药物由西雅图遗传学英语Seagen公司开发。[4]

参考资料

[编辑]
  1. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Dacetuzumab页面存档备份,存于互联网档案馆), American Medical Association.
  2. ^ Advani R, Forero-Torres A, Furman RR, Rosenblatt JD, Younes A, Ren H, et al. Phase I study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma. Journal of Clinical Oncology. September 2009, 27 (26): 4371–7. PMID 19636010. doi:10.1200/JCO.2008.21.3017可免费查阅. 
  3. ^ Khubchandani S, Czuczman MS, Hernandez-Ilizaliturri FJ. Dacetuzumab, a humanized mAb against CD40 for the treatment of hematological malignancies. Current Opinion in Investigational Drugs. June 2009, 10 (6): 579–87. PMID 19513947. 
  4. ^ Khubchandani, Sapna; Czuczman, Myron S.; Hernandez-Ilizaliturri, Francisco J. Dacetuzumab, a humanized mAb against CD40 for the treatment of hematological malignancies. Current Opinion in Investigational Drugs (London, England: 2000). 2009-06, 10 (6) [2024-03-10]. ISSN 2040-3429. PMID 19513947. (原始内容存档于2024-03-10).