Protein-coding gene in the species Homo sapiens
DnaJ homolog subfamily C member 1 is a protein that in humans is encoded by the DNAJC1 gene .[ 5]
DNAJC1 has been shown to interact with Alpha 1-antichymotrypsin .[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000136770 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026740 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1" .^ Kroczynska B, Evangelista CM, Samant SS, Elguindi EC, Blond SY (2004). "The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity" . J. Biol. Chem . 279 (12): 11432–43. doi :10.1074/jbc.M310903200 PMC 1553221 PMID 14668352 . Kroczynska B, King-Simmons L, Alloza L, et al. (2006). "BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4". Biochem. Biophys. Res. Commun . 338 (3): 1467–77. doi :10.1016/j.bbrc.2005.10.101 . PMID 16271702 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10" . Nature . 429 (6990): 375–81. Bibcode :2004Natur.429..375D . doi :10.1038/nature02462 PMID 15164054 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Kroczynska B, Evangelista CM, Samant SS, et al. (2004). "The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity" . J. Biol. Chem . 279 (12): 11432–43. doi :10.1074/jbc.M310903200 PMC 1553221 PMID 14668352 . Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics . 83 (1): 153–67. doi :10.1016/S0888-7543(03)00235-0 . PMID 14667819 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Chevalier M, Rhee H, Elguindi EC, Blond SY (2000). "Interaction of murine BiP/GRP78 with the DnaJ homologue MTJ1" . J. Biol. Chem . 275 (26): 19620–7. doi :10.1074/jbc.M001333200 PMC 1534116 PMID 10777498 . PDBe-KB provides an overview of all the structure information available in the PDB for Human DnaJ homolog subfamily C member 1
PDB gallery
2cqq : Solution Structure of RSGI RUH-037, a myb DNA-binding domain in human cDNA
2cqr : Solution structure of RSGI RUH-043, a myb DNA-binding domain in human cDNA
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