LY-310762

LY-310762
Identifiers
	IUPAC name 3,3-Dimethyl-1-(2-[4-(4-fluorobenzoyl)piperidin-1-yl]-1-ethyl)-1,3-dihydro-2H-indol-2-one;
CAS Number	192927-92-7;
PubChem CID	4282258;
ChemSpider	3488832;
ChEBI	CHEBI:140937;
CompTox Dashboard (EPA)	DTXSID701126571 ;
Chemical and physical data
Formula	C24H27FN2O2
Molar mass	394.490 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c3cc(F)ccc3C(=O)C2CCN(CC2)CCN1C(=O)C(C)(C)c4c1cccc4;
	InChI InChI=1S/C24H27FN2O2/c1-24(2)20-5-3-4-6-21(20)27(23(24)29)16-15-26-13-11-18(12-14-26)22(28)17-7-9-19(25)10-8-17/h3-10,18H,11-16H2,1-2H3; Key:KDXISMANFPJVJY-UHFFFAOYSA-N;
	(verify)

LY-310762 is a drug which acts as a potent and selective antagonist for the 5-HT_1D serotonin receptor, with reasonable selectivity over the closely related 5-HT_1B subtype.^[1]

References

^ Pullar IA, Boot JR, Broadmore RJ, Eyre TA, Cooper J, Sanger GJ, Wedley S, Mitchell SN (June 2004). "The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig". European Journal of Pharmacology. 493 (1–3): 85–93. doi:10.1016/j.ejphar.2004.04.029. PMID 15189767.

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

[pmid15189767-1] Pullar IA, Boot JR, Broadmore RJ, Eyre TA, Cooper J, Sanger GJ, Wedley S, Mitchell SN (June 2004). "The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig". European Journal of Pharmacology. 493 (1–3): 85–93. doi:10.1016/j.ejphar.2004.04.029. PMID 15189767.

[1]

Identifiers

IUPAC name 3,3-Dimethyl-1-(2-[4-(4-fluorobenzoyl)piperidin-1-yl]-1-ethyl)-1,3-dihydro-2H-indol-2-one
CAS Number	192927-92-7
PubChem CID	4282258
ChemSpider	3488832
ChEBI	CHEBI:140937
CompTox Dashboard (EPA)	DTXSID701126571
Chemical and physical data
Formula	C₂₄H₂₇FN₂O₂
Molar mass	394.490 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c3cc(F)ccc3C(=O)C2CCN(CC2)CCN1C(=O)C(C)(C)c4c1cccc4
InChI InChI=1S/C24H27FN2O2/c1-24(2)20-5-3-4-6-21(20)27(23(24)29)16-15-26-13-11-18(12-14-26)22(28)17-7-9-19(25)10-8-17/h3-10,18H,11-16H2,1-2H3 Key:KDXISMANFPJVJY-UHFFFAOYSA-N
(verify)